Malaria biology

Malaria biology

The Malaria Biology Laboratory seeks to identify and characterise novel parasite proteins for their suitability as both Malaria drug and vaccine targets.

We have a major focus on invasion of the human red blood cell by the small invasive merozoite stage of the parasite lifecycle as a therapeutic target.

By developing therapeutics such as drugs and vaccines that inhibit merozoite invasion of the red blood cell, we can instantly disrupt the lifecycle of the parasite in the stage that causes all the symptoms of the disease.

RCID Danny Wilson Figure 1

Figure 1

We apply a breakthrough P. falciparum merozoite purification method to study this previously intractable lifecycle stage (Figure 1).

We are also searching for novel drug targets that inhibit growth of P. falciparum and the zoonotic human malaria parasite P. knowlesi throughout the blood stage lifecycle.

People and publications