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Synthetic biology applications of enzymes
Honours project: Use approaches to generate enzyme catalyst based systems to develop greener and sustainable processes for the production of useful and high value chemicals.
Deciphering the catalytic potential & the electron transfer pathways of microorganisms
![Electron transfer pathways](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/bell-electron-transfer-pathways-2.png?h=b3a32e4e&itok=_eCbBz59)
Honours project: Study new enzymes and the associated ferredoxins from bacteria found in interesting environments (or genes from metagenomes) or which carry out novel reactions.
Synthesis using Nature’s catalysts; enzymes
![Stephen Bell Biocatalyst 2](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/stephen-ball-biocatalysis2.png?h=4bf7da95&itok=pv-5gDNK)
Honours project: Projects in this area involve the isolation and study new enzymes from bacteria of interest or taking existing enzymes and adapting them for chemical synthesis.
[Read more about Synthesis using Nature’s catalysts; enzymes]
Understanding the mechanism of enzyme catalysed reactions of importance in drug metabolism
![Stephen Bell - Mechanism of enzyme catalysed reactions of importance in drug metabolism](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/stephen-bell-mechanism-enzyme1.png?h=d69a50e9&itok=JJReL70d)
Honours project: Learn about the mechanism by which the major family of enzymes involved in drug metabolism catalyse oxidative transformations.
Improving food safety using plasma sterilisation
![Improving food safety using plasma sterilisation](/sites/default/files/styles/ua_landscape/public/media/images/2019-09/coad-honours-plasma.jpg?h=7e824dc5&itok=zBX2Hj8G)
Honours project: Investigate the use of a high energy form of matter (plasma) to improve food safety.
[Read more about Improving food safety using plasma sterilisation]
Group B Strep & oxidative stress
![Dr Stephen Kidd](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/stephen-kidd-lab.jpg?h=34477e30&itok=bHzuNOTK)
Honours project: Identify the response of Group B Streptococcus to relevant reactive oxygen and reactive nitrogen species.
Staphylococcus aureus & lifestyle variations
![Stephen Kidd Staph](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/stephen-kidd-staph.png?h=62529416&itok=tpFNi6Xs)
Honours project: Conduct biomedical research into Staphylococcus aureus (Golden staph).
[Read more about Staphylococcus aureus & lifestyle variations]
Mixed colony biofilms & disease outcome
Honours project: This molecular and biomedical science honours project explores mixed colony biofilms and their relationship to disease outcomes.
Role of eEF2K & cancer cell migration & invasion
![Cancer cells survive and gain the ability to spread under microenvironmental stress conditions through the inhibition of mTORC1 and subsequent activation of eEF2K](/sites/default/files/styles/ua_landscape/public/media/images/2019-06/proud-figure1-cancer-cells-survive.png?h=d470be75&itok=uM8YIUca)
Honours project: Study cell signalling and gene regulation through the exploration of the role of eukaryotic elongation factor 2 kinase (eEF2K) and cancer cell migration and invasion.
[Read more about Role of eEF2K & cancer cell migration & invasion]
Unwrapping the 3D genome to map autoimmune disease
Honours project: Help unravel the chromatin interactome to map the genetic risk of type 1 diabetes.
[Read more about Unwrapping the 3D genome to map autoimmune disease]