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Role of HIFs in cancer

Decipher the specific roles of HIF1 and HIF2 in multiple myeloma.

Honours project: Decipher the specific roles of HIF1 and HIF2 in multiple myeloma.

[Read more about Role of HIFs in cancer]

Directed evolution of proteins in vivo

Honours project: Use a new phage-based directed evolution approach to evolve proteins with properties to make them suitable for use in synthetic circuit applications, such as in vivo biosensing or construction of bistable switches.

[Read more about Directed evolution of proteins in vivo]

Synthetic phage therapy

Synthetic phage therapy

Honours project: Investigate the structural biology of bacteriophage proteins.

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Identifying new drugs that kill parasites

Honours project: Work with a team of researchers who are identifying and characterising novel drugs that kill apicomplexan parasites.

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Deciphering & exploiting bacterial cholesterol metabolism to combat disease

Deciphering & exploiting bacterial cholesterol metabolism to combat disease

Honours project: Address the fundamental science behind the use of the steroid cholesterol as a source of energy by bacteria.

[Read more about Deciphering & exploiting bacterial cholesterol metabolism to combat disease]

Deciphering the catalytic potential & the electron transfer pathways of microorganisms

Electron transfer pathways

Honours project: Study new enzymes and the associated ferredoxins from bacteria found in interesting environments (or genes from metagenomes) or which carry out novel reactions.

[Read more about Deciphering the catalytic potential & the electron transfer pathways of microorganisms]

Synthetic biology applications of enzymes

Honours project: Use approaches to generate enzyme catalyst based systems to develop greener and sustainable processes for the production of useful and high value chemicals.

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Understanding the mechanism of enzyme catalysed reactions of importance in drug metabolism

Stephen Bell - Mechanism of enzyme catalysed reactions of importance in drug metabolism

Honours project: Learn about the mechanism by which the major family of enzymes involved in drug metabolism catalyse oxidative transformations.

[Read more about Understanding the mechanism of enzyme catalysed reactions of importance in drug metabolism]

Synthesis using Nature’s catalysts; enzymes

Stephen Bell Biocatalyst 2

Honours project: Projects in this area involve the isolation and study new enzymes from bacteria of interest or taking existing enzymes and adapting them for chemical synthesis.

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Improving food safety using plasma sterilisation

Improving food safety using plasma sterilisation

Honours project: Investigate the use of a high energy form of matter (plasma) to improve food safety.

[Read more about Improving food safety using plasma sterilisation]

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