News: Honours projects - Molecular and biomedical science: Genetics

Cellular-stress induced activation of non-TFEB regulated lysosomal genes

Cellular stress-induced transactivation of autophagy and lysosomal genes. In normal conditions, transcription factor EB (TFEB) is kept in the cytoplasm in an inactive form.

Honours project: Investigate the role of the eIF2α/ATF4 pathway in stress-induced transcription of non-TFEB genes.

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Investigating molecular mechanisms of disease

Honours project: Characterise molecular and cellular changes driving improvements to disease outcomes after postnatal 17B-estradiol treatment in mice modeling intellectual disability and seizures. 

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Echidna biology for conservation, wildlife management & habitat monitoring

Echidna research

Honours project: This project investigates the molecular basis of echidna biology for application in conservation, wildlife management and habitat monitoring.

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Do MPS patient derived stem cells form bone and cartilage?

Honours project: This project in genetics and molecular pathology examines the characterisation of patient derived stem cells.

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Neurogenetics

Honours project: Help understand the biology of human brain function by studying major neurological disorders which are genetically determined. 

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WWOX Enzyme function is a target for treatment of metabolic diseases including cancer

Honours project: This genetics research project will explore the WWOX Enzyme function as a target for the treatment of metabolic diseases including cancer.

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‘Non-self’ & organelle quality control mutations

Honours project: Explore a project in ‘Non-self’ and organelle quality control mutations: late-onset neurodegeneration is an auto-inflammatory disease.

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Drosophila model for mucopolysaccharidosis type III

Honours project: Use the unique capabilities of Drosophila to model and genetically dissect pathogenic pathways that lead from mutation to clinical symptoms in mucopolysaccharidosis type III.

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Hill-Robertson interference, the Red Queen and the evolution of sex

Study the evolution of sex

Honours project: This evolutionary genetics honours project explores the Hill-Robertson interference, the Red Queen and the evolution of sex.

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Testing the gamete competition theory of the evolution of anisogamy

Study the evolution of sex

Honours project: Explore genetics and evolutionary biology by testing the gamete competition theory of the evolution of anisogamy.

[Read more about Testing the gamete competition theory of the evolution of anisogamy]

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