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Deciphering the catalytic potential & the electron transfer pathways of microorganisms

Honours project: Study new enzymes and the associated ferredoxins from bacteria found in interesting environments (or genes from metagenomes) or which carry out novel reactions.
Identifying new drugs that kill parasites
Honours project: Work with a team of researchers who are identifying and characterising novel drugs that kill apicomplexan parasites.
Directed evolution of proteins in vivo
Honours project: Use a new phage-based directed evolution approach to evolve proteins with properties to make them suitable for use in synthetic circuit applications, such as in vivo biosensing or construction of bistable switches.
Synthetic phage therapy

Honours project: Investigate the structural biology of bacteriophage proteins.
Synthesis using Nature’s catalysts; enzymes

Honours project: Projects in this area involve the isolation and study new enzymes from bacteria of interest or taking existing enzymes and adapting them for chemical synthesis.
[Read more about Synthesis using Nature’s catalysts; enzymes]
Understanding the mechanism of enzyme catalysed reactions of importance in drug metabolism

Honours project: Learn about the mechanism by which the major family of enzymes involved in drug metabolism catalyse oxidative transformations.
Improving food safety using plasma sterilisation

Honours project: Investigate the use of a high energy form of matter (plasma) to improve food safety.
[Read more about Improving food safety using plasma sterilisation]
Role of eEF2K & cancer cell migration & invasion

Honours project: Study cell signalling and gene regulation through the exploration of the role of eukaryotic elongation factor 2 kinase (eEF2K) and cancer cell migration and invasion.
[Read more about Role of eEF2K & cancer cell migration & invasion]
Group B Strep & oxidative stress

Honours project: Identify the response of Group B Streptococcus to relevant reactive oxygen and reactive nitrogen species.
Staphylococcus aureus & lifestyle variations

Honours project: Conduct biomedical research into Staphylococcus aureus (Golden staph).
[Read more about Staphylococcus aureus & lifestyle variations]