News: Honours projects - Molecular and biomedical science: Biochemistry
Exploring the functions of MAPK-interacting kinases (MNKs) in metabolic disease
![MNKs play a key role in promoting adipocyte differentiation and this will be explored using the 3T3-L1 system](/sites/default/files/styles/ua_landscape/public/media/images/2019-06/proud-figure-mnks.png?h=29a9ff9b&itok=IYCRw7Qu)
Honours project: Explore the functions of MAPK-interacting kinases (MNKs) in metabolic disease at the South Australian Health and Medical Research Institute.
[Read more about Exploring the functions of MAPK-interacting kinases (MNKs) in metabolic disease]
CRISPR therapy development
Honours project: This genome editing project focuses on developing CRISPR gene therapy for Duchenne Muscular Dystrophy (DMD).
What causes PCDH19-epilepsy?
Honours project: Develop a stronger understanding of the pathological mechanism of PCDH19-girls clustering epilepsy.
Development of CRISPR gene drive technology in mice
Honours project: Explore CRISPR gene drives to modify native or invasive pest populations to benefit human health, ecosystems or agriculture.
[Read more about Development of CRISPR gene drive technology in mice]
Blinatumomab in relapsed acute lymphoblastic leukaemia
![Lymphoblastic Leukaemia](/sites/default/files/styles/ua_landscape/public/media/images/2019-08/Lymphoblastosis_in_Acute_Lymphoblastic_Leukaemia.jpg?h=aa81dfca&itok=k-2as_tS)
Honours project: Investigate resistance mechanisms to the bispecific T-cell engager (BiTE) blinatumomab in relapsed acute lymphoblastic leukaemia.
[Read more about Blinatumomab in relapsed acute lymphoblastic leukaemia]
Cloning acute lymphoblastic leukaemia fusion genes and variants
![Acute lymphoblastic Leukaemia](/sites/default/files/styles/ua_landscape/public/media/images/2019-08/Acute_lymphoblastic_leukaemia.jpg?h=aa81dfca&itok=hMQvSfjD)
Honours project: Clone full-length fusion-genes and gene variants from patient material into mammalian expression plasmids.
[Read more about Cloning acute lymphoblastic leukaemia fusion genes and variants]