News: Honours projects - Molecular and biomedical science
Role of HIFs in cancer
Honours project: Decipher the specific roles of HIF1 and HIF2 in multiple myeloma.
Directed evolution of proteins in vivo
Honours project: Use a new phage-based directed evolution approach to evolve proteins with properties to make them suitable for use in synthetic circuit applications, such as in vivo biosensing or construction of bistable switches.
Synthetic phage therapy
Honours project: Investigate the structural biology of bacteriophage proteins.
Identifying new drugs that kill parasites
Honours project: Work with a team of researchers who are identifying and characterising novel drugs that kill apicomplexan parasites.
Deciphering & exploiting bacterial cholesterol metabolism to combat disease
Honours project: Address the fundamental science behind the use of the steroid cholesterol as a source of energy by bacteria.
[Read more about Deciphering & exploiting bacterial cholesterol metabolism to combat disease]
Synthetic biology applications of enzymes
Honours project: Use approaches to generate enzyme catalyst based systems to develop greener and sustainable processes for the production of useful and high value chemicals.
Deciphering the catalytic potential & the electron transfer pathways of microorganisms
Honours project: Study new enzymes and the associated ferredoxins from bacteria found in interesting environments (or genes from metagenomes) or which carry out novel reactions.
Synthesis using Nature’s catalysts; enzymes
Honours project: Projects in this area involve the isolation and study new enzymes from bacteria of interest or taking existing enzymes and adapting them for chemical synthesis.
[Read more about Synthesis using Nature’s catalysts; enzymes]
Understanding the mechanism of enzyme catalysed reactions of importance in drug metabolism
Honours project: Learn about the mechanism by which the major family of enzymes involved in drug metabolism catalyse oxidative transformations.
Group B Strep & oxidative stress
Honours project: Identify the response of Group B Streptococcus to relevant reactive oxygen and reactive nitrogen species.
