News: Honours projects - Molecular and biomedical science
Evaluation of monoclonal antibodies in detection of avian influenza antigens
![Chickens, Roseworthy](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/chickens-371.jpg?h=f9eda97d&itok=VzBDEefN)
Honours project: Evaluate different recombinant and non-recombinant monoclonal antibodies against M2e antigen of avian influenza virus, to find the most reactive antigens and antibodies
[Read more about Evaluation of monoclonal antibodies in detection of avian influenza antigens]
Cellular-stress induced activation of non-TFEB regulated lysosomal genes
![Cellular stress-induced transactivation of autophagy and lysosomal genes. In normal conditions, transcription factor EB (TFEB) is kept in the cytoplasm in an inactive form.](/sites/default/files/styles/ua_landscape/public/media/images/2019-06/proud-figure-cellular-stress.png?h=5a854f77&itok=BsDzr49I)
Honours project: Investigate the role of the eIF2α/ATF4 pathway in stress-induced transcription of non-TFEB genes.
[Read more about Cellular-stress induced activation of non-TFEB regulated lysosomal genes]
Exploring the functions of MAPK-interacting kinases (MNKs) in metabolic disease
![MNKs play a key role in promoting adipocyte differentiation and this will be explored using the 3T3-L1 system](/sites/default/files/styles/ua_landscape/public/media/images/2019-06/proud-figure-mnks.png?h=29a9ff9b&itok=IYCRw7Qu)
Honours project: Explore the functions of MAPK-interacting kinases (MNKs) in metabolic disease at the South Australian Health and Medical Research Institute.
[Read more about Exploring the functions of MAPK-interacting kinases (MNKs) in metabolic disease]
Investigating molecular mechanisms of disease
Honours project: Characterise molecular and cellular changes driving improvements to disease outcomes after postnatal 17B-estradiol treatment in mice modeling intellectual disability and seizures.
[Read more about Investigating molecular mechanisms of disease]
Echidna biology for conservation, wildlife management & habitat monitoring
![Echidna research](/sites/default/files/styles/ua_landscape/public/media/images/2019-03/echidna.jpg?h=5e55bd74&itok=9sRWjUVe)
Honours project: This project investigates the molecular basis of echidna biology for application in conservation, wildlife management and habitat monitoring.
[Read more about Echidna biology for conservation, wildlife management & habitat monitoring]
Do MPS patient derived stem cells form bone and cartilage?
Honours project: This project in genetics and molecular pathology examines the characterisation of patient derived stem cells.
[Read more about Do MPS patient derived stem cells form bone and cartilage?]
How the body clears a medically important fungal pathogen
Honours project: This immunopathology research project studies innate immunity in the killing of the fungal pathogen, Candida albicans by human phagocytes.
[Read more about How the body clears a medically important fungal pathogen]
Complement receptor immunoglobulin - infection & immunity & inflammation
![Characteristics, function and expression of complement receptors](/sites/default/files/styles/ua_landscape/public/media/images/2019-06/ferrante-figure-receptors.png?h=3418f72d&itok=lYMgqCPa)
Honours project: Examine the complement receptor immunoglobulin expression in human macrophages and its role in infection and immunity and inflammation.
[Read more about Complement receptor immunoglobulin - infection & immunity & inflammation]
Role of the Actin-Related Protein Complex 1B (ARPC1B) in neutrophil antimicrobial function
![The Arp2/3 complex is one of the major protein complexes in actin polymerisation and cellular motility.](/sites/default/files/styles/ua_landscape/public/media/images/2019-06/ferrante-arp23-complex.png?h=bfb44aff&itok=1uj_ujAR)
Honours project: Investigate the role of the Actin-Related Protein Complex 1B (ARPC1B) in neutrophil antimicrobial function.
CRISPR therapy development
Honours project: This genome editing project focuses on developing CRISPR gene therapy for Duchenne Muscular Dystrophy (DMD).