News: Honours projects - Molecular and biomedical science
Drosophila model for mucopolysaccharidosis type III
Honours project: Use the unique capabilities of Drosophila to model and genetically dissect pathogenic pathways that lead from mutation to clinical symptoms in mucopolysaccharidosis type III.
[Read more about Drosophila model for mucopolysaccharidosis type III]
TLR4 & Treg cells in early pregnancy
Honours project: This reproductive immunology project explores the role of the toll like receptor 4 (TLR4) in maternal immune adaptation for pregnancy.
Immune regulation of preterm birth
Honours project: This honours project in molecular and biomedical science will investigate immune regulation of preterm birth.
Cloning acute lymphoblastic leukaemia fusion genes and variants
![Acute lymphoblastic Leukaemia](/sites/default/files/styles/ua_landscape/public/media/images/2019-08/Acute_lymphoblastic_leukaemia.jpg?h=aa81dfca&itok=hMQvSfjD)
Honours project: Clone full-length fusion-genes and gene variants from patient material into mammalian expression plasmids.
[Read more about Cloning acute lymphoblastic leukaemia fusion genes and variants]
Efficacy of a combination of TKI and a novel allosteric inhibitor asciminib in chronic myeloid leukaemia
![Tim Hughes honours - asciminib](/sites/default/files/styles/ua_landscape/public/media/images/2019-09/hughes-honours-asciminib.png?h=6ef8a005&itok=nvsZtdkJ)
Honours project: Investigate the synergistic effect of the combination of TKI and asciminib.
Monitoring of minimal residual disease on chronic myeloid leukaemia patients in a setting of treatment free remission
![hughes honours myeloid leukaemia](/sites/default/files/styles/ua_landscape/public/media/images/2019-09/hughes-honours-myeloid-leukaemia.png?h=c223e903&itok=Fe0wMRtp)
Honours project: Characterise the residual leukaemia population in TFR patients, and understand why some patients relapse and others don’t.
Metabolic dependencies for improved therapeutic outcomes in chronic myeloid leukaemia
![hughes honours myeloid leukaemia](/sites/default/files/styles/ua_landscape/public/media/images/2019-09/hughes-honours-myeloid-leukaemia2.png?h=aaee32ba&itok=ao0qgvFJ)
Honours project: Participate in a novel and innovative approach will likely provide a combinational treatment strategy with greater efficacy than current approaches.
Viable, but non-culturable bacteria: Understanding the risks for food safety
![Salmonella species growing on X.L.D. agar Nathan Reading [CC BY-NC-ND 2.0]](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/salmonella.jpg?h=0d6ba564&itok=jRXiht6q)
Honours project: This project aims to determine the ability of viable but non culturable bacteria to cause disease.
[Read more about Viable, but non-culturable bacteria: Understanding the risks for food safety]
Isolation & evaluation of protein pattern of koala retroviruses
![Koala, Cleland](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/koala-10914.jpg?h=6981f79a&itok=iys5II52)
Honours project: Determine the antigenic pattern of isolated Koala retroviruses in South Australia.
[Read more about Isolation & evaluation of protein pattern of koala retroviruses]
Full genome sequencing of recombinant strains of canine hepatitis
![DNA sequencing](/sites/default/files/styles/ua_landscape/public/media/images/2019-05/dna-sequencing-22859.jpg?h=2f83cd36&itok=ZnAMkV1f)
Honours project: Full genome sequencing will be performed to find the genomic structure of a new infectious canine hepatitis virus.
[Read more about Full genome sequencing of recombinant strains of canine hepatitis]