News: Honours projects - Molecular and biomedical science

Staphylococcus aureus & lifestyle variations

Stephen Kidd Staph

Honours project: Conduct biomedical research into Staphylococcus aureus (Golden staph).

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Mixed colony biofilms & disease outcome

Honours project: This molecular and biomedical science honours project explores mixed colony biofilms and their relationship to disease outcomes.

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Role of eEF2K & cancer cell migration & invasion

Cancer cells survive and gain the ability to spread under microenvironmental stress conditions through the inhibition of mTORC1 and subsequent activation of eEF2K

Honours project: Study cell signalling and gene regulation through the exploration of the role of eukaryotic elongation factor 2 kinase (eEF2K) and cancer cell migration and invasion.

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Unwrapping the 3D genome to map autoimmune disease

Honours project: Help unravel the chromatin interactome to map the genetic risk of type 1 diabetes.

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Systematic analysis of the eIF4E interactome

Active mTORC1 phosphorylates 4E-BP, preventing 4E1 binding. (B) mTORC1 inhibition leads to 4E-BP hypophosphorylation; 4E-BP now binds 4E1 and blocks eIF4F

Honours project: Conduct a systematic analysis of the eIF4E interactome to understand the distinct functional roles of the three mammalian eIF4E proteins in translation initiation.

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Understanding the molecular mechanisms of intellectual disability

Honours project: Investigate the role IQSEC2 and synaptic morphology and plasticity on the orchestration of the complex architecture required for ‘normal’ cognition.

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Genetic mutations associated with skin & wool growth in sheep

Animal science sheep

Honours project: Identify genetic mutations in sheep DSC1 & DSG4 genes essential for skin and wool follicle architecture.

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Uncovering the relationship between two malaria proteins required for invasion

Honours project: Delve into an honours project in the structural and functional analysis of malaria proteins required for Red Blood Cell invasion.

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Occurrence & distribution of ticks in South Australia

Tick

Honours project: Outbreaks of the tick-transmitted parasitic disease Theileriosis in South Australia has raised questions regarding the presence of the tick vector.

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Pathogenesis of newly emerged Newcastle disease virus in South East Asia

Chicken Roseworthy

Honours project: Investigate molecular basis of pathogenicity of the Newcastle disease virus and provide preliminary information to develop new vaccines for protection of poultry in Indonesia.

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